Drug General Information |
Drug ID |
D0Q7LD
|
Former ID |
DNC002645
|
Drug Name |
2-Methyl-2-Propanol
|
Drug Type |
Small molecular drug
|
Indication |
Discovery agent
|
Investigative |
[1]
|
Structure |
|
Download
2D MOL
3D MOL
|
Formula |
C4H10O
|
Canonical SMILES |
CC(C)(C)O
|
InChI |
1S/C4H10O/c1-4(2,3)5/h5H,1-3H3
|
InChIKey |
DKGAVHZHDRPRBM-UHFFFAOYSA-N
|
PubChem Compound ID |
|
PubChem Substance ID |
587060, 820565, 824488, 824493, 824495, 829409, 831395, 831718, 837274, 854655, 3132278, 6467454, 7890706, 8023088, 8154051, 10534928, 12079254, 14709186, 15146291, 17425442, 24851330, 24858660, 24859879, 24862169, 24867672, 24870757, 24873382, 24892081, 26697099, 26703480, 26706548, 26710884, 26719397, 29225374, 30964600, 37451913, 37609869, 37615327, 46507480, 48409757, 48409762, 48413335, 48414942, 48416814, 48420525, 48424140, 49854267, 57309692, 57323401, 57410735
|
Target and Pathway |
Target(s) |
Calmodulin |
Target Info |
Inhibitor |
[1]
|
Methionine aminopeptidase 2 |
Target Info |
Inhibitor |
[1]
|
KEGG Pathway
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Ras signaling pathway
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Rap1 signaling pathway
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Calcium signaling pathway
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cGMP-PKG signaling pathway
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cAMP signaling pathway
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Phosphatidylinositol signaling system
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Oocyte meiosis
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Adrenergic signaling in cardiomyocytes
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Vascular smooth muscle contraction
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Circadian entrainment
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Long-term potentiation
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Neurotrophin signaling pathway
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Dopaminergic synapse
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Olfactory transduction
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Phototransduction
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Inflammatory mediator regulation of TRP channels
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Insulin signaling pathway
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GnRH signaling pathway
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Estrogen signaling pathway
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Melanogenesis
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Oxytocin signaling pathway
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Glucagon signaling pathway
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Salivary secretion
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Gastric acid secretion
|
Alzheimer's disease
|
Amphetamine addiction
|
Alcoholism
|
Pertussis
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Tuberculosis
|
Glioma
|
NetPath Pathway
|
RANKL Signaling Pathway
|
TSH Signaling Pathway
|
PANTHER Pathway
|
CCKR signaling map ST
|
Pathway Interaction Database
|
BCR signaling pathway
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p38 MAPK signaling pathway
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Calcineurin-regulated NFAT-dependent transcription in lymphocytes
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Role of Calcineurin-dependent NFAT signaling in lymphocytes
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IL2 signaling events mediated by PI3K
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IFN-gamma pathway
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Lissencephaly gene (LIS1) in neuronal migration and development
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ErbB1 downstream signaling
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VEGFR1 specific signals
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Regulation of cytoplasmic and nuclear SMAD2/3 signaling
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Calcium signaling in the CD4+ TCR pathway
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Signaling events mediated by VEGFR1 and VEGFR2
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Insulin-mediated glucose transport
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N-cadherin signaling events
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Cellular roles of Anthrax toxin
|
Regulation of Ras family activation
|
Downstream signaling in naï
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PathWhiz Pathway
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Muscle/Heart Contraction
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Reactome
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Calmodulin induced events
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Platelet degranulation
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Translocation of GLUT4 to the plasma membrane
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Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
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DARPP-32 events
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eNOS activation
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Inactivation, recovery and regulation of the phototransduction cascade
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FCERI mediated Ca+2 mobilization
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Ca2+ pathway
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CREB phosphorylation through the activation of CaMKII
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Ras activation uopn Ca2+ infux through NMDA receptor
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Smooth Muscle Contraction
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VEGFR2 mediated vascular permeability
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VEGFR2 mediated cell proliferation
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RHO GTPases activate IQGAPs
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RAF/MAP kinase cascade
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Antigen activates B Cell Receptor (BCR) leading to generation of second messengersR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
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WikiPathways
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Translocation of GLUT4 to the Plasma Membrane
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Visual phototransduction
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Fc epsilon receptor (FCERI) signaling
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Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
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Signaling by the B Cell Receptor (BCR)
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Inositol phosphate metabolism
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DAG and IP3 signaling
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Opioid Signalling
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Muscle contraction
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Metabolism of nitric oxide
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Metabolism of carbohydrates
|
References |
REF 1 | How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. |