Drug Information

Drug General Information
Drug ID
D0Q8CE
Former ID
DNC010835
Drug Name
4-(2-(3-tert-Butylphenylamino)ethyl)-1H-imidazole
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530846]
Structure
Download
2D MOL

3D MOL
Formula
C15H21N3
Canonical SMILES
CC(C)(C)C1=CC(=CC=C1)NCCC2=CN=CN2
InChI
1S/C15H21N3/c1-15(2,3)12-5-4-6-13(9-12)17-8-7-14-10-16-11-18-14/h4-6,9-11,17H,7-8H2,1-3H3,(H,16,18)
InChIKey
LRIVTYQQFCXAFC-UHFFFAOYSA-N
PubChem Compound ID
46222046
Target and Pathway
Target(s) Histamine H3 receptor Target Info Inhibitor [530846]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Histamine receptors
G alpha (i) signalling events
WikiPathways Monoamine Transport
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 530846J Med Chem. 2010 May 13;53(9):3840-4.Role of hydrophobic substituents on the terminal nitrogen of histamine in receptor binding and agonist activity: development of an orally active histamine type 3 receptor agonist and evaluation of its antistress activity in mice.
Ref 530846J Med Chem. 2010 May 13;53(9):3840-4.Role of hydrophobic substituents on the terminal nitrogen of histamine in receptor binding and agonist activity: development of an orally active histamine type 3 receptor agonist and evaluation of its antistress activity in mice.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.