Drug Information

Drug General Information
Drug ID
D0Q8DM
Former ID
DIB008014
Drug Name
BIM-26226
Synonyms
D-Pentafluorophenylalanyl-L-glutaminyl-L-tryptophyl-L-alanyl-L-valyl-D-alanyl-L-histidyl-L-leucine methyl ester; (D-Pentafluorophenylalanyl6,D-alanyl11)bombesin (6-13) methyl ester
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Discontinued in Phase 1 [545685]
Structure
Download
2D MOL
CAS Number
CAS 136207-23-3
Target and Pathway
Target(s) Gastrin-releasing peptide receptor Target Info Modulator [534659]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCRs, Other
References
Ref 545685Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004166)
Ref 534659Effect of the gastrin-releasing peptide antagonist BIM 26226 and lanreotide on an acinar pancreatic carcinoma. Eur J Pharmacol. 1998 Apr 17;347(1):77-86.

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