Drug General Information
Drug ID	D0Q8NO
Former ID	DIB021202
Drug Name	VUF 8328
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[538760]
Structure		Download 2D MOL
Formula	C7H12N4S
InChI	InChI=1S/C7H12N4S/c8-7(9)12-3-1-2-6-4-10-5-11-6/h4-5H,1-3H2,(H3,8,9)(H,10,11)
InChIKey	QJUVWGBVEFRHCN-UHFFFAOYSA-N
PubChem Compound ID	10176414
PubChem Substance ID	15171398, 24443430, 40265995, 47434796, 48105129, 49846726, 78828582, 103184401, 135651313, 163139369
Target and Pathway
Target(s)	Histamine H3 receptor	Target Info	Agonist	[526200]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Histamine receptors
	G alpha (i) signalling events
WikiPathways	Monoamine Transport
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 538760	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1246).
Ref 526200	Constitutive activity of histamine h(3) receptors stably expressed in SK-N-MC cells: display of agonism and inverse agonism by H(3) antagonists. J Pharmacol Exp Ther. 2001 Dec;299(3):908-14.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.