Drug Information

Drug General Information
Drug ID
D0Q8VM
Former ID
DNCL002930
Drug Name
TT-401
Indication Type 2 diabetes [ICD9: 250; ICD10:E11] Phase 2 [549337]
Company
Transition Therapeutics
Target and Pathway
Target(s) Glucagon-like peptide 1 receptor Target Info Modulator [532497]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Insulin secretion
Reactome Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
G alpha (s) signalling events
Glucagon-type ligand receptors
WikiPathways GPCRs, Class B Secretin-like
Integration of energy metabolism
GPCR ligand binding
GPCR downstream signaling
References
Ref 549337Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800035378)
Ref 532497Relationship between systemic cytokines and complement factor H Y402H polymorphism in patients with dry age-related macular degeneration. Am J Ophthalmol. 2013 Dec;156(6):1176-83.

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