Drug Information

Drug General Information
Drug ID
D0QH0B
Former ID
DNC000611
Drug Name
EPI-2010
Drug Type
Antisense drug
Indication Asthma [ICD10:J45] Discontinued in Phase 2 [546639]
Therapeutic Class
Antisense
CAS Number
CAS 402848-82-2
Target and Pathway
Target(s) mRNA of adenosine A1 receptor Target Info [535309]
NetPath Pathway TCR Signaling Pathway
RANKL Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome Adenosine P1 receptors
G alpha (i) signalling events
References
Ref 546639Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009338)
Ref 535309RASONs: a novel antisense oligonucleotide therapeutic approach for asthma. Expert Opin Biol Ther. 2001 Nov;1(6):979-83.

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