Drug Information
Drug General Information | |||||
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Drug ID |
D0R1JI
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Former ID |
DPR000101
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Drug Name |
Rottlerin
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Synonyms |
Kamalin; Mallotoxin; R 5648; BMK1-F10; (E)-1-(6-((3-Acetyl-2,4,6-trihydroxy-5-methylphenyl)methyl)-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-8-yl)-3-phenyl-2-propen-1-one; (E)-1-[6-[(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)methyl]-5,7-dihydroxy-2,2-dimethylchromen-8-yl]-3-phenylprop-2-en-1-one; 1-[6-(3-Acetyl-2,4,6-trihydroxy-5-methyl-benzyl)-5,7-dihydroxy-2,2-dimethyl-2H-chromen-8-yl]-3-phenyl-propenone; 1-[6-[(3-Acetyl-2,4,6-trihydroxy-5-methylphenyl)methyl]-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-8-yl]-3-phenyl-2-propen-1-one; 1-[6-[(3-Acetyl-2,4,6-trihydroxy-5-methylphenyl)methyl]-5,7-dihydroxy-2,2-dimethylchromen-8-yl]-3-phenylprop-2-en-1-one
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Drug Type |
Small molecular drug
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Structure |
Download2D MOL |
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Formula |
C30H28O8
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InChI |
InChI=1S/C30H28O8/c1-15-24(33)19(27(36)22(16(2)31)25(15)34)14-20-26(35)18-12-13-30(3,4)38-29(18)23(28(20)37)21(32)11-10-17-8-6-5-7-9-17/h5-13,33-37H,14H2,1-4H3/b11-10+
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InChIKey |
DEZFNHCVIZBHBI-ZHACJKMWSA-N
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CAS Number |
CAS 82-08-6
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PubChem Compound ID | |||||
PubChem Substance ID |
12904, 105770, 399681, 3153150, 8616811, 14762702, 17405610, 24278679, 26752221, 26752222, 26759460, 29204544, 39315440, 46391355, 46499867, 47440005, 47515095, 47662030, 47885185, 48034855, 48258970, 48483334, 49863415, 50104906, 50104907, 50104908, 50104909, 53521727, 53778158, 53789304, 57358417, 71822747, 74381038, 85789037, 85789464, 90340883, 91722237, 92303370, 92310076, 99300988, 99302508, 103210193, 104018897, 104051642, 109816921, 113856047, 121361810, 124557942, 124634337, 124887042
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Target and Pathway | |||||
Target(s) | Protein kinase C | Target Info | Inhibitor | [536923] | |
References | |||||
Ref 536923 | Drugs used to treat Parkinson's disease, present status and future directions. CNS Neurol Disord Drug Targets. 2008 Oct;7(4):321-42. | ||||
Ref 539687 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2611). |
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