Drug General Information
Drug ID	D0R2LS
Former ID	DNC008665
Drug Name	SR-125543A
Indication	Discovery agent		Investigative	[529622]
Structure		Download 2D MOL 3D MOL
Target and Pathway
Target(s)	Corticotropin releasing factor receptor 1	Target Info	Inhibitor	[529622]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Long-term depression
NetPath Pathway	TNFalpha Signaling Pathway
PANTHER Pathway	Cortocotropin releasing factor receptor signaling pathway
Reactome	Class B/2 (Secretin family receptors)
	G alpha (s) signalling events
WikiPathways	GPCRs, Class B Secretin-like
	Myometrial Relaxation and Contraction Pathways
	Corticotropin-releasing hormone
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 529622	Bioorg Med Chem Lett. 2008 Aug 15;18(16):4486-90. Epub 2008 Jul 18.2-Arylpyrimidines: novel CRF-1 receptor antagonists.
Ref 529622	Bioorg Med Chem Lett. 2008 Aug 15;18(16):4486-90. Epub 2008 Jul 18.2-Arylpyrimidines: novel CRF-1 receptor antagonists.

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