Drug Information
Drug General Information | |||||
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Drug ID |
D0R2TW
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Former ID |
DIB019988
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Drug Name |
GW848687X
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Synonyms |
GW 848687X; GW-848687X
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [540317] | ||
Structure |
Download2D MOL |
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Formula |
C24H18ClF2NO3
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InChI |
InChI=1S/C24H18ClF2NO3/c25-15-8-10-23(31-13-14-7-9-16(26)12-20(14)27)19(11-15)17-3-1-4-18(17)21-5-2-6-22(28-21)24(29)30/h2,5-12H,1,3-4,13H2,(H,29,30)
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InChIKey |
PFODPHDNBFSMOX-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Prostaglandin E2 receptor, EP1 subtype | Target Info | Antagonist | [528512] | |
PANTHER Pathway | PI3 kinase pathway | ||||
References | |||||
Ref 528512 | The discovery of 6-[2-(5-chloro-2-{[(2,4-difluorophenyl)methyl]oxy}phenyl)-1-cyclopenten-1-yl]-2-pyridinecarboxylic acid, GW848687X, a potent and selective prostaglandin EP1 receptor antagonist for the treatment of inflammatory pain. Bioorg Med Chem Lett. 2007 Jan 15;17(2):385-9. Epub 2006 Oct 20. |
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