Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0R3OR
|
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| Former ID |
DIB016655
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| Drug Name |
SR-27950
|
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| Synonyms |
SR-27899
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| Indication | Eating disorder [ICD9: 278, 307.5, 401, 428.0; ICD10:E66, F50, I10-I16, I50] | Terminated | [1] | ||
| Company |
Sanofi
|
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
n1(c(C(=O)N[C@H]2N=C(c3c(NC2=O)cccc3)c2ccccc2)cc2c1cccc<br />2)CC(=O)O
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| Target and Pathway | |||||
| Target(s) | Cholecystokinin receptor type A | Target Info | Modulator | [2] | |
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Insulin secretion | |||||
| Pancreatic secretion | |||||
| Reactome | Peptide ligand-binding receptors | ||||
| G alpha (q) signalling events | |||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| Peptide GPCRs | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001260) | ||||
| REF 2 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 76). | ||||
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