Drug Information

Drug General Information
Drug ID
D0R6MJ
Former ID
DNCL002636
Drug Name
MORAb-009
Synonyms
Amatuximab
Drug Type
Antibody
Indication Mesothelioma [ICD9: 163; ICD10:C45] Phase 2 [522179], [542714]
Company
Eisai
Target and Pathway
Target(s) Mesothelin-ADC Target Info [532964], [550415]
NetPath Pathway TCR Signaling Pathway
References
Ref 522179ClinicalTrials.gov (NCT00570713) An Efficacy Study of MORAb-009 in Subjects With Pancreatic Cancer. U.S. National Institutes of Health.
Ref 542714(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7750).
Ref 532964Phase II clinical trial of amatuximab, a chimeric antimesothelin antibody with pemetrexed and cisplatin in advanced unresectable pleural mesothelioma. Clin Cancer Res. 2014 Dec 1;20(23):5927-36.
Ref 550415National Cancer Institute Drug Dictionary (drug id 543500).

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