Drug General Information
Drug ID	D0R7GH
Former ID	DIB009208
Drug Name	CS-526
Synonyms	AKU-517; R-105266
Indication	Gastroesophageal reflux disease [ICD9: 140-229, 530; ICD10:K21]		Discontinued in Phase 1	[547339]
Company	Sankyo Co Ltd
Structure		Download 2D MOL 3D MOL
Canonical SMILES	c12n(C[C@@H]3[C@H](C3)C)c(c(c1cnnc2OCc1ccc(cc1)F)C)C
Target and Pathway
Target(s)	H+ K+ ATPase	Target Info	Modulator	[528949]
References
Ref 547339	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015294)
Ref 528949	Pharmacological profile of novel acid pump antagonist 7-(4-fluorobenzyloxy)-2,3-dimethyl-1-{[(1S,2S)-2-methyl cyclopropyl]methyl}-1H-pyrrolo[2,3-d]pyridazine (CS-526). J Pharmacol Exp Ther. 2007 Oct;323(1):308-17. Epub 2007 Jul 13.

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