Drug General Information
Drug ID	D0S0EQ
Former ID	DIB013717
Drug Name	AZD-0865
Synonyms	AR-H044277
Drug Type	Small molecular drug
Indication	Gastrointestinal disease [ICD10:K00-K93]		Phase 2	[521710]
Company	AstraZeneca plc
Structure		Download 2D MOL 3D MOL
Formula	C21H26N4O2
Canonical SMILES	c12n(cc(cc1NCc1c(cccc1C)C)C(=O)NCCO)c(c(n2)C)C
PubChem Compound ID	9951066
Target and Pathway
Target(s)	H+ K+ ATPase	Target Info	Modulator	[528510]
References
Ref 521710	ClinicalTrials.gov (NCT00206284) A Dose-finding Phase IIb Study With AZD0865 and Esomeprazole in GERD Patients Without Erosive Esophagitis.. U.S. National Institutes of Health.
Ref 528510	Mechanism of action of AZD0865, a K+-competitive inhibitor of gastric H+,K+-ATPase. Biochem Pharmacol. 2007 Jan 15;73(2):198-205. Epub 2006 Sep 24.

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