Drug Information

Drug General Information
Drug ID
D0S0FZ
Former ID
DCL000739
Drug Name
Carisbamate
Synonyms
Comfyde; JNJ 10234094; RWJ 333369; YKP 509; Carisbamate (USAN); JNJ-10234094; RWJ-333369; YKP-509; S-2-O-Carbamoyl-1-o-chlorophenyl-ethanol; [(2S)-2-(2-chlorophenyl)-2-hydroxyethyl] carbamate
Drug Type
Small molecular drug
Indication Epilepsy; Focal; Seizure disorder [ICD9: 345, 345.4, 345.5, 345.9, 780.3; ICD10:G40, G40.2, P90, R56] Phase 3 [536934]
Company
Johnson & Johnson
Structure
Download
2D MOL

3D MOL
Formula
C9H10ClNO3
Canonical SMILES
C1=CC=C(C(=C1)C(COC(=O)N)O)Cl
InChI
1S/C9H10ClNO3/c10-7-4-2-1-3-6(7)8(12)5-14-9(11)13/h1-4,8,12H,5H2,(H2,11,13)/t8-/m1/s1
InChIKey
OLBWFRRUHYQABZ-MRVPVSSYSA-N
CAS Number
CAS 194085-75-1
PubChem Compound ID
6918474
PubChem Substance ID
12015336, 14818877, 15172026, 17194912, 43529844, 47208229, 57371948, 79488142, 114788030, 128824565, 134223530, 134339232, 135213416, 140097639, 160670319, 164837840, 184528548, 198974092, 198991959, 223366886, 225025837, 227016974, 247473631, 252552117
SuperDrug ATC ID
N03AX19
Target and Pathway
Target(s) Sodium channel Target Info Blocker [536498], [536845], [536934]
KEGG Pathway Dopaminergic synapse
Reactome Interaction between L1 and Ankyrins
References
Ref 536934Progress report on new antiepileptic drugs: a summary of the Ninth Eilat Conference (EILAT IX). Epilepsy Res. 2009 Jan;83(1):1-43. Epub 2008 Nov 12.
Ref 536498Emerging drugs for epilepsy. Expert Opin Emerg Drugs. 2007 Sep;12(3):407-22.
Ref 536845Pharmacological management of epilepsy: recent advances and future prospects. Drugs. 2008;68(14):1925-39.
Ref 536934Progress report on new antiepileptic drugs: a summary of the Ninth Eilat Conference (EILAT IX). Epilepsy Res. 2009 Jan;83(1):1-43. Epub 2008 Nov 12.

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