Drug Information

Drug General Information
Drug ID
D0S3XL
Former ID
DIB020522
Drug Name
neuromedin B
Drug Type
Small molecular drug
Indication Discovery agent Investigative [541341]
Structure
Download
2D MOL
Formula
C52H73N15O12S
InChI
InChI=1S/C52H73N15O12S/c1-27(2)17-36(64-51(78)40(21-41(54)69)61-42(70)22-53)48(75)66-38(19-31-23-57-34-14-10-9-13-33(31)34)47(74)60-28(3)46(73)67-44(29(4)68)52(79)58-25-43(71)62-39(20-32-24-56-26-59-32)50(77)65-37(18-30-11-7-6-8-12-30)49(76)63-35(45(55)72)15-16-80-5/h6-14,23-24,26-29,35-40,44,57,68H,15-22,25,53H2,1-5H3,(H2,54,69)(H2,55,72)(H,56,59)(H,58,79)(H,60,74)(H,61,70)(H,62,71)(H,63,76)(H,64,78)(H,65,77)(H,66,75)(H,67,73)
InChIKey
YPFNACALNKVZNK-UHFFFAOYSA-N
PubChem Compound ID
4345957
PubChem Substance ID
6392559, 24897661, 35646532, 79733795, 85088100, 112882973, 135651812, 162091354, 179293761
Target and Pathway
Target(s) Gastrin-releasing peptide receptor Target Info Agonist [533765]
Bombesin receptor Target Info Agonist [533243]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interactionhsa04080:Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (q) signalling eventsR-HSA-375276:Peptide ligand-binding receptors
G alpha (q) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 541341(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 613).
Ref 533243Insights into bombesin receptors and ligands: Highlighting recent advances. Peptides. 2015 May 11. pii: S0196-9781(15)00145-X.
Ref 533765Expression and characterization of cloned human bombesin receptors. Mol Pharmacol. 1995 Jan;47(1):10-20.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.