Drug General Information
Drug ID
D0S7KQ
Former ID
DCL000319
Drug Name
Hematide
Indication Anemia [ICD9: 280-285; ICD10:D50-D64] Phase 3 [551985]
Company
Affymax Inc; Takeda Pharmaceutical Co Ltd.
CAS Number
CAS 910576-32-8
Target and Pathway
Target(s) Erythropoietin Receptor Target Info Agonist [531837], [532210], [537308]
KEGG Pathway Cytokine-cytokine receptor interaction
PI3K-Akt signaling pathway
Jak-STAT signaling pathway
Hematopoietic cell lineage
NetPath Pathway TGF_beta_Receptor Signaling Pathway
Pathway Interaction Database Signaling events mediated by Stem cell factor receptor (c-Kit)
EPO signaling pathway
WikiPathways EPO Receptor Signaling
References
Ref 551985Clinical pipeline report, company report or official report of Takeda.
Ref 531837Peginesatide and erythropoietin stimulate similar erythropoietin receptor-mediated signal transduction and gene induction events. Exp Hematol. 2012 Jul;40(7):575-87.
Ref 532210Nat Rev Drug Discov. 2013 Feb;12(2):87-90.
Ref 537308Anemia in chronic kidney disease: status of new therapies. Curr Opin Nephrol Hypertens. 2009 Mar;18(2):112-5.

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