TTD | Drug: D0S7VN

Drug General Information
Drug ID	D0S7VN
Former ID	DIB009253
Drug Name	MRL-953
Synonyms	SDZ-MRL-953
Indication	Immune disorder [ICD10:D80-D89]		Terminated	[545071]
Company	Novartis AG
Structure		Download 2D MOL 3D MOL
Canonical SMILES	[C@H]1([C@@H]([C@H]([C@@H]([C@H](O1)CO)OC(=O)C[C@H](O)C<br />CCCCCCCCCC)OC(=O)C[C@H](O)CCCCCCCCCCC)NC(=O)C[C@H](O)CC<br />CCCCCCCCC)OP(=O)(O)O
CAS Number	CAS 123136-61-8
Target and Pathway
Target(s)	Interleukin-1 receptor, type II	Target Info	Agonist	[534068]
KEGG Pathway	MAPK signaling pathway
	Cytokine-cytokine receptor interaction
	Hematopoietic cell lineage
	Amoebiasis
	HTLV-I infection
	Transcriptional misregulation in cancer
NetPath Pathway	IL1 Signaling Pathway
NetPath Pathway	TNFalpha Signaling Pathway
Pathway Interaction Database	IL1-mediated signaling events
Reactome	Interleukin-1 signaling
WikiPathways	MAPK Signaling Pathway
	Interleukin-1 signaling
	Apoptosis Modulation and Signaling
References
Ref 545071	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002036)
Ref 534068	SDZ MRL 953, a lipid A analog as selective cytokine inducer. Prog Clin Biol Res. 1995;392:549-65.

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Drug Information