Drug General Information
Drug ID	D0S8UN
Former ID	DNC002717
Drug Name	12-Phenylheme
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[551393]
Structure		Download 2D MOL
Formula	C40H38FeN4O4
PubChem Compound ID	5287448
Target and Pathway
Target(s)	Heme oxygenase	Target Info	Inhibitor	[551393]
BioCyc Pathway	Heme degradation
KEGG Pathway	Porphyrin and chlorophyll metabolism
	HIF-1 signaling pathway
	Mineral absorption
	MicroRNAs in cancer
Pathway Interaction Database	Validated transcriptional targets of AP1 family members Fra1 and Fra2
	HIF-1-alpha transcription factor network
PathWhiz Pathway	Porphyrin Metabolism
Reactome	Iron uptake and transport
WikiPathways	Oxidative Stress
	Transcriptional activation by NRF2
	NRF2 pathway
	Nuclear Receptors Meta-Pathway
	miR-targeted genes in squamous cell - TarBase
	miR-targeted genes in muscle cell - TarBase
	miR-targeted genes in lymphocytes - TarBase
	miR-targeted genes in leukocytes - TarBase
	miR-targeted genes in epithelium - TarBase
References
Ref 551393	How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393	How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.