TTD | Drug: D0SE4D

Drug General Information
Drug ID	D0SE4D
Former ID	DIB003188
Drug Name	Org-20599
Synonyms	Org-20549
Drug Type	Small molecular drug
Indication	Anesthesia [ICD9: 338; ICD10:R20.0]		Terminated	[545545]
Company	Organon BioSciences
Structure		Download 2D MOL 3D MOL
Formula	C25H40ClNO3
Canonical SMILES	[C@@]12([C@@H]3[C@H]([C@H]4[C@@]([C@H](CC4)C(=O)CCl)(CC<br />3)C)CC[C@H]2C[C@@H]([C@H](C1)N1CCOCC1)O)C.S(=O)(=O)(O)C
CAS Number	CAS 187652-71-7
PubChem Compound ID	656747
Target and Pathway
Target(s)	GABA A receptor delta subunit	Target Info	Modulator	[534312]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Retrograde endocannabinoid signaling
	GABAergic synapse
	Morphine addiction
	Nicotine addiction
References
Ref 545545	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003651)
Ref 534312	The anaesthetic action and modulation of GABAA receptor activity by the novel water-soluble aminosteroid Org 20599. Neuropharmacology. 1996;35(9-10):1209-22.

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Drug Information