Drug General Information
Drug ID
D0SQ1T
Former ID
DNC010937
Drug Name
2,5-dideoxy-2,5-imino-D-altritol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530905]
Structure
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2D MOL

3D MOL

Formula
C6H13NO4
Canonical SMILES
C(C1C(C(C(N1)CO)O)O)O
InChI
1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4-,5-,6+/m1/s1
InChIKey
PFYHYHZGDNWFIF-KAZBKCHUSA-N
PubChem Compound ID
Target and Pathway
Target(s) Lactase-phlorizin hydrolase Target Info Inhibitor [530905]
Alpha-galactosidase A Target Info Inhibitor [530905]
KEGG Pathway Galactose metabolism
Metabolic pathways
Carbohydrate digestion and absorptionhsa00052:Galactose metabolism
Glycerolipid metabolism
Sphingolipid metabolism
Glycosphingolipid biosynthesis - globo series
Lysosome
PathWhiz Pathway Lactose Degradation
Galactose MetabolismPW000148:Sphingolipid Metabolism
Galactose Metabolism
Reactome Glycosphingolipid metabolism
WikiPathways Metabolism of carbohydratesWP2788:Sphingolipid metabolism
References
Ref 530905Bioorg Med Chem. 2010 Jun 1;18(11):3790-4. Epub 2010 Apr 21.2,5-Dideoxy-2,5-imino-d-altritol as a new class of pharmacological chaperone for Fabry disease.
Ref 530905Bioorg Med Chem. 2010 Jun 1;18(11):3790-4. Epub 2010 Apr 21.2,5-Dideoxy-2,5-imino-d-altritol as a new class of pharmacological chaperone for Fabry disease.

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