Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D0T3HY
|
||||
Former ID |
DAP000268
|
||||
Drug Name |
Levorphanol
|
||||
Synonyms |
Antalgin; Aromarone; Cetarin; DEXTRORPHAN; Dromoran; Levodroman; Levorfanol; Levorfanolo; Levorphan; Levorphanolum; Methorfinan; Methorphinan; Orphan; Racemethorphanum; Racemorfano; Racemorphan; Racemorphane; Racemorphanum; Levorfanolo [DCIT]; Methorfinan [Czech]; Racemic dromoran; NU 2206; L-Dromoran; Levorfanol [INN-Spanish]; Levorphanol (INN); Levorphanolum [INN-Latin]; Racemorfano [INN-Spanish]; Racemorphan [INN:BAN]; Racemorphane [INN-French]; Racemorphanum [INN-Latin]; Ro 1-5431; Levo-Dromoran (TN); N-Methyl-3-hydroxymorphinan; Dl-3-Hydroxy-N-methylmorphinan; (+)-3-Hydroxy-17-methylmorphinan; (+-)-17-Methylmorphinan-3-ol; (+-)-3-Hydroxy-N-methylmorphinan; (-)-3-Hydroxy-N-methylmorphinan; (-)-N-Methylmorphinan-3-ol; 1,3,4,9,10,10a-Hexahydro-11-methyl-2H-10,4a-iminoethanophenanthren-6-ol, dl-mixture; 1,3,4,9,10,10a-Hexahydro-6-hydroxy-2H-10,4a-(iminoethano)-11-methylphenanthrene; 17-Methylmorphinan-3-ol; 3-Hydroxy-N-methylmorphinan
|
||||
Drug Type |
Small molecular drug
|
||||
Indication | Moderate to severe pain [ICD10:R52, G89] | Approved | [1] | ||
Therapeutic Class |
Analgesics
|
||||
Company |
Roxane Laboratories
|
||||
Structure |
Download2D MOL |
||||
Formula |
C17H23NO
|
||||
InChI |
InChI=1S/C17H23NO/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17/h5-6,11,14,16,19H,2-4,7-10H2,1H3/t14-,16+,17+/m0/s1
|
||||
InChIKey |
JAQUASYNZVUNQP-USXIJHARSA-N
|
||||
CAS Number |
CAS 77-07-6
|
||||
PubChem Compound ID | |||||
PubChem Substance ID |
10214, 15020649, 24724648, 32961206, 46506558, 48416172, 49992831, 49993032, 57362766, 76028106, 96024813, 103928501, 123085530, 128247583, 134223222, 134337582, 134339944, 134972148, 135017293, 136350398, 137004972, 142097602, 160848620, 160964195, 175266678, 179116756, 198937435, 223365930, 223440165, 224186944, 226412710, 250137238, 252351126
|
||||
Target and Pathway | |||||
Target(s) | Opioid receptor | Target Info | Agonist | [2] | |
References | |||||
REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | ||||
REF 2 | Comparison of the effects of dextromethorphan, dextrorphan, and levorphanol on the hypothalamo-pituitary-adrenal axis. J Pharmacol Exp Ther. 2004 May;309(2):515-22. Epub 2004 Jan 23. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.