Drug General Information
Drug ID
D0T3HY
Former ID
DAP000268
Drug Name
Levorphanol
Synonyms
Antalgin; Aromarone; Cetarin; DEXTRORPHAN; Dromoran; Levodroman; Levorfanol; Levorfanolo; Levorphan; Levorphanolum; Methorfinan; Methorphinan; Orphan; Racemethorphanum; Racemorfano; Racemorphan; Racemorphane; Racemorphanum; Levorfanolo [DCIT]; Methorfinan [Czech]; Racemic dromoran; NU 2206; L-Dromoran; Levorfanol [INN-Spanish]; Levorphanol (INN); Levorphanolum [INN-Latin]; Racemorfano [INN-Spanish]; Racemorphan [INN:BAN]; Racemorphane [INN-French]; Racemorphanum [INN-Latin]; Ro 1-5431; Levo-Dromoran (TN); N-Methyl-3-hydroxymorphinan; Dl-3-Hydroxy-N-methylmorphinan; (+)-3-Hydroxy-17-methylmorphinan; (+-)-17-Methylmorphinan-3-ol; (+-)-3-Hydroxy-N-methylmorphinan; (-)-3-Hydroxy-N-methylmorphinan; (-)-N-Methylmorphinan-3-ol; 1,3,4,9,10,10a-Hexahydro-11-methyl-2H-10,4a-iminoethanophenanthren-6-ol, dl-mixture; 1,3,4,9,10,10a-Hexahydro-6-hydroxy-2H-10,4a-(iminoethano)-11-methylphenanthrene; 17-Methylmorphinan-3-ol; 3-Hydroxy-N-methylmorphinan
Drug Type
Small molecular drug
Indication Moderate to severe pain [ICD10:R52, G89] Approved [1]
Therapeutic Class
Analgesics
Company
Roxane Laboratories
Structure
Download
2D MOL

3D MOL

Formula
C17H23NO
InChI
InChI=1S/C17H23NO/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17/h5-6,11,14,16,19H,2-4,7-10H2,1H3/t14-,16+,17+/m0/s1
InChIKey
JAQUASYNZVUNQP-USXIJHARSA-N
CAS Number
CAS 77-07-6
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Opioid receptor Target Info Agonist [2]
References
REF 1Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
REF 2Comparison of the effects of dextromethorphan, dextrorphan, and levorphanol on the hypothalamo-pituitary-adrenal axis. J Pharmacol Exp Ther. 2004 May;309(2):515-22. Epub 2004 Jan 23.

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