Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0T7WL
|
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| Former ID |
DIB012775
|
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| Drug Name |
Pirmenol
|
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| Synonyms |
Pimenol; Pirmavar; Pirmenol hydrochloride
|
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| Drug Type |
Small molecular drug
|
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| Indication | Heart arrhythmia [ICD10:I47-I49] | Approved | [551871] | ||
| Company |
Pfizer Inc
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C22H30N2O
|
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| Canonical SMILES |
N1([C@H](CCC[C@H]1C)C)CCCC(c1ncccc1)(c1ccccc1)O.Cl
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Sodium channel | Target Info | Modulator | [531502], [551871] | |
| KEGG Pathway | Dopaminergic synapse | ||||
| Reactome | Interaction between L1 and Ankyrins | ||||
| References | |||||
| Ref 531502 | Pirmenol, a new antiarrhythmic drug with potassium- and sodium-channel blocking activity; a voltage-clamp study in rabbit Purkinje fibres. Naunyn Schmiedebergs Arch Pharmacol. 1990 May;341(5):462-71. | ||||
| Ref 551871 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | ||||
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