Drug General Information
Drug ID	D0TC5E
Former ID	DIB018567
Drug Name	2-methylhistamine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[538783]
Structure		Download 2D MOL 3D MOL
Formula	C7H15N3O3S
InChI	InChI=1S/C7H15N3O3S/c11-2-1-8-3-9(5-12)7(14)10(4-8)6-13/h11-13H,1-6H2
InChIKey	ZGUKXHGPXOTTSU-UHFFFAOYSA-N
PubChem Compound ID	92613
PubChem Substance ID	44423426, 50966028, 103141917, 104407893, 117402976, 126428224, 135049237, 135649707, 162874411
Target and Pathway
Target(s)	Histamine H4 receptor	Target Info	Agonist	[527985]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Histamine receptors
	G alpha (i) signalling events
WikiPathways	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 538783	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1268).
Ref 527985	Compared pharmacology of human histamine H3 and H4 receptors: structure-activity relationships of histamine derivatives. Br J Pharmacol. 2006 Apr;147(7):744-54.

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