Drug Information
Drug General Information | |||||
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Drug ID |
D0TG1H
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Former ID |
DIB001554
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Drug Name |
Diclofenac
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Synonyms |
Diclofenac (sodium matrix patch, pain)
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Drug Type |
Small molecular drug
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Indication | Osteoarthritis of knee [ICD10:M15-M19, M47] | Approved | [1] | ||
Unspecified | Investigative | [2], [1] | |||
Therapeutic Class |
Neurology Agents
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Company |
Novartis Pharmaceuticals Corp
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Structure |
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Download2D MOL |
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Formula |
C14H11Cl2NO2
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InChI |
InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19)
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InChIKey |
DCOPUUMXTXDBNB-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
4831, 641516, 827876, 832709, 837582, 5394317, 7887044, 7979066, 8027112, 8149635, 8151929, 10509002, 11335447, 11335577, 11360686, 11360816, 11363824, 11364719, 11366386, 11367281, 11368948, 11369843, 11371489, 11372884, 11374190, 11375443, 11377110, 11378007, 11461658, 11461788, 11466622, 11467742, 11484817, 11486423, 11488807, 11490201, 11492321, 11494744, 14873560, 24424557, 29214789, 29222179, 46393862, 46504644, 46513484, 47365081, 47365082, 47662173, 47885304, 48184892
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Target and Pathway | |||||
Target(s) | Cyclooxygenase | Target Info | Modulator | [2], [1] | |
References | |||||
REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | ||||
REF 2 | Diclofenac and NS-398, a selective cyclooxygenase-2 inhibitor, decrease agonist-induced contractions of the pig isolated ureter. Urol Res. 2000 Dec;28(6):376-82. | ||||
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