Drug Information

Drug General Information
Drug ID
D0TT9H
Former ID
DIB020574
Drug Name
NS3763
Synonyms
NS-3763
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467611]
Structure
Download
2D MOL
Formula
C22H16N2O6
InChI
InChI=1S/C22H16N2O6/c25-19(13-7-3-1-4-8-13)23-17-12-18(16(22(29)30)11-15(17)21(27)28)24-20(26)14-9-5-2-6-10-14/h1-12H,(H,23,25)(H,24,26)(H,27,28)(H,29,30)
InChIKey
UUDYZUDTQPLDDP-UHFFFAOYSA-N
PubChem Compound ID
4359312
PubChem Substance ID
6418632, 9652709, 14879364, 24724545, 26753220, 29215129, 35659234, 47834786, 57356952, 79017318, 91055844, 103403720, 104027300, 107792993, 112919391, 135698084, 141483629, 162248586, 162651961, 170485613, 178101091, 181850651, 184587837, 227304825, 244205635, 252156341
Target and Pathway
Target(s) Glutamate receptor, ionotropic kainate 1 Target Info Antagonist [543831]
KEGG Pathway Neuroactive ligand-receptor interaction
Glutamatergic synapse
PANTHER Pathway Huntington disease
Ionotropic glutamate receptor pathway
Metabotropic glutamate receptor group III pathway
Metabotropic glutamate receptor group I pathway
WikiPathways Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
References
Ref 467611(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4274).
Ref 543831(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 450).

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