Drug General Information
Drug ID	D0TZ8C
Former ID	DNC004509
Drug Name	6-(2-Imidazol-1-yl-vinyl)-1H-quinolin-2-one
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[526726]
Structure		Download 2D MOL 3D MOL
Formula	C14H11N3O
Canonical SMILES	C1=CC2=C(C=CC(=O)N2)C=C1C=CN3C=CN=C3
InChI	1S/C14H11N3O/c18-14-4-2-12-9-11(1-3-13(12)16-14)5-7-17-8-6-15-10-17/h1-10H,(H,16,18)/b7-5+
InChIKey	ULTZJAJIZBBKSG-FNORWQNLSA-N
PubChem Compound ID	14373279
Target and Pathway
Target(s)	CGMP-inhibited 3',5'-cyclic phosphodiesterase A	Target Info	Inhibitor	[526726]
KEGG Pathway	Purine metabolism
	cGMP-PKG signaling pathway
	cAMP signaling pathway
	Morphine addiction
Reactome	cGMP effects
	G alpha (s) signalling events
WikiPathways	miR-targeted genes in muscle cell - TarBase
	miR-targeted genes in lymphocytes - TarBase
References
Ref 526726	J Med Chem. 1992 Feb 21;35(4):620-8.3,4-Dihydroquinolin-2(1H)-ones as combined inhibitors of thromboxane A2 synthase and cAMP phosphodiesterase.
Ref 526726	J Med Chem. 1992 Feb 21;35(4):620-8.3,4-Dihydroquinolin-2(1H)-ones as combined inhibitors of thromboxane A2 synthase and cAMP phosphodiesterase.

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