Drug General Information
Drug ID
D0U0HX
Former ID
DIB007209
Drug Name
Molgramostim
Synonyms
Genfulin; Molgramostim (topical, wound healing); Molgramostim (topical, wound healing), GeneScience; GM-CSF (topical, woundhealing), GeneScience; Granulocyte-macrophage colony stimulating factor (topical, wound healing), GeneScience
Indication Wound healing [ICD10:T14.0-T14.1] Phase 1 [525225]
Company
GeneScience Pharmaceuticals Co Ltd
Target and Pathway
Target(s) Granulocyte-macrophage colony-stimulating factor receptor alpha chain Target Info Agonist [550807]
KEGG Pathway Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
Hematopoietic cell lineage
Pathways in cancer
NetPath Pathway IL3 Signaling Pathway
RANKL Signaling Pathway
Pathway Interaction Database GMCSF-mediated signaling events
Alpha9 beta1 integrin signaling events
Reactome GPVI-mediated activation cascade
G beta:gamma signalling through PI3Kgamma
Interleukin-3, 5 and GM-CSF signaling
RAF/MAP kinase cascade
Surfactant metabolism
Interleukin receptor SHC signaling
WikiPathways Interleukin-2 signaling
Interleukin-3, 5 and GM-CSF signaling
References
Ref 525225ClinicalTrials.gov (NCT02468908) Inhaled Molgramostim (rhGM-CSF) in Healthy Adult Subjects.
Ref 550807Clinical pipeline report, company report or official report of gensci-china.

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