Drug Information

Drug General Information
Drug ID
D0U0YR
Former ID
DPR000109
Drug Name
SNAP-7941
Synonyms
Snap7941
Drug Type
Small molecular drug
Indication Obesity; Anxiety; Depression [ICD9: 278, 300, 311; ICD10:E66, F32, F40-F42] Preclinical [536122], [538804]
Company
Synaptic
Structure
Download
2D MOL

3D MOL
Formula
C31H37F2N5O6
InChI
InChI=1S/C31H37F2N5O6/c1-19(39)35-23-7-4-6-21(16-23)20-10-14-37(15-11-20)13-5-12-34-30(41)38-28(22-8-9-24(32)25(33)17-22)27(29(40)44-3)26(18-43-2)36-31(38)42/h4,6-9,16-17,20,28H,5,10-15,18H2,1-3H3,(H,34,41)(H,35,39)(H,36,42)/t28-/m0/s1
InChIKey
FWMHZWMPUWAUPL-NDEPHWFRSA-N
CAS Number
CAS 387825-78-7
PubChem Compound ID
11520239
PubChem Substance ID
56427147, 76443901, 80954629, 103453248, 104040521, 135651061, 163340456, 223863759, 231461213
Target and Pathway
Target(s) Melanin-concentrating hormone receptor 1 Target Info Antagonist [536122]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 536122Emerging drugs for obesity: linking novel biological mechanisms to pharmaceutical pipelines. Expert Opin Emerg Drugs. 2005 Aug;10(3):643-60.
Ref 538804(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1313).
Ref 536122Emerging drugs for obesity: linking novel biological mechanisms to pharmaceutical pipelines. Expert Opin Emerg Drugs. 2005 Aug;10(3):643-60.

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