Drug General Information
Drug ID
D0U1BU
Former ID
DIB002246
Drug Name
HPP-851
Synonyms
11-beta HSD-1 (metabolic disorders), High Point; 11-beta HSD-1 (metabolic disorders), TransTech Pharma; 11-beta hydroxysteroid dehydrogenase-1 inhibitors (metabolic disorders), Novo Nordisk; 11-beta hydroxysteroid dehydrogenase-1 inhibitors (metabolic disorders), TransTech Pharma
Indication Metabolic disorders [ICD9: 270-279; ICD10:E70-E89] Preclinical [548697]
Company
Novo Nordisk A/S
Target and Pathway
Target(s) Corticosteroid 11-beta-dehydrogenase, isozyme 1 Target Info Inhibitor [548698]
KEGG Pathway Steroid hormone biosynthesis
Metabolism of xenobiotics by cytochrome P450
Metabolic pathways
Chemical carcinogenesis
NetPath Pathway IL1 Signaling Pathway
FSH Signaling Pathway
PathWhiz Pathway Steroidogenesis
Reactome Glucocorticoid biosynthesis
WikiPathways Prostaglandin Synthesis and Regulation
Metabolism of steroid hormones and vitamin D
Glucocorticoid & Mineralcorticoid Metabolism
References
Ref 548697Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027759)
Ref 548698Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027759)

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