Drug Information

Drug General Information
Drug ID
D0U5SI
Former ID
DAP000516
Drug Name
Procainamide
Synonyms
Biocoryl; Novocainamid; Novocainamide; Novocamid; Procainamida; Procainamidum; Procamide; Procan; Procanbid; Procapan; Pronestyl; Novocaine amide; Procaine amide; P-Aminobenzoic diethylaminoethylamide; Procainamida [INN-Spanish]; Procainamide (INN); Procainamide [INN:BAN]; Procainamidum [INN-Latin]; Procan (TN); Procanbid (TN); Procapan (free base); Pronestyl (TN); Pronestyl-Sr; P-Amino-N-(2-diethylaminoethyl)benzamide; Benzamide, 4-amino-N-(2-(diethylamino)ethyl)-(9CI); 2-Diethylaminoethylamid kyseliny p-aminobenzoove; 2-Diethylaminoethylamid kyseliny p-aminobenzoove [Czech]; 4-Amino-N-(2-(Diethylamino)Ethyl)Benzamide Sulfate; 4-Amino-N-(2-(diethylamino)ethyl)benzamide; 4-Amino-N-[2-(diethylamino)ethyl]benzamide; 4-amino-N-(2-diethylaminoethyl)-benzamide; 4-amino-N-(2-diethylaminoethyl)benzamide
Drug Type
Small molecular drug
Indication Ventricular arrhythmias [ICD9: 427.1; ICD10:I47.2] Approved [468043], [538376]
Therapeutic Class
Antiarrhythmic Agents
Structure
Download
2D MOL

3D MOL
Formula
C13H21N3O
InChI
InChI=1S/C13H21N3O/c1-3-16(4-2)10-9-15-13(17)11-5-7-12(14)8-6-11/h5-8H,3-4,9-10,14H2,1-2H3,(H,15,17)
InChIKey
REQCZEXYDRLIBE-UHFFFAOYSA-N
CAS Number
CAS 51-06-9
PubChem Compound ID
4913
PubChem Substance ID
9605, 87927, 3138733, 3296200, 5227620, 7980387, 8153024, 10524666, 11111690, 11111691, 11120271, 11120759, 11121247, 11121528, 11122008, 11132695, 11336106, 11361345, 11362597, 11363730, 11365159, 11366292, 11367721, 11368854, 11370465, 11370466, 11371829, 11373322, 11374112, 11375883, 11377016, 11382660, 11462317, 11466365, 11467485, 11485065, 11486030, 11489111, 11490371, 11492302, 11494650, 15220788, 26751611, 26751612, 29223991, 46507313, 47216907, 47440400, 47662439, 47810893
ChEBI ID
ChEBI:8428
SuperDrug ATC ID
C01BA02
SuperDrug CAS ID
cas=000051069
Target and Pathway
Target(s) E3 ubiquitin protein ligase COP1 Target Info Modulator [556264]
KEGG Pathway p53 signaling pathway
Ubiquitin mediated proteolysis
PANTHER Pathway P53 pathway feedback loops 1
Pathway Interaction Database ATM pathway
Direct p53 effectors
p53 pathway
References
Ref 468043(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4811).
Ref 538376FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 089257.
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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