Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0U7HJ
|
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| Former ID |
DNAP001404
|
||||
| Drug Name |
Certoparin sodium
|
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| Synonyms |
Alphaparin (TN)
|
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| Indication | Deep vein thrombosis [ICD9: 437.6, 453, 453.40, 671.5, 671.9; ICD10:I80-I82, I80.2] | Approved | [551871] | ||
| Target and Pathway | |||||
| Target(s) | Coagulation factor Xa | Target Info | Modulator | [525658], [534676], [536361] | |
| KEGG Pathway | Complement and coagulation cascades | ||||
| PANTHER Pathway | Blood coagulation | ||||
| Pathway Interaction Database | Beta2 integrin cell surface interactions | ||||
| PathWhiz Pathway | Coagulation | ||||
| Reactome | Extrinsic Pathway of Fibrin Clot Formation | ||||
| Intrinsic Pathway of Fibrin Clot Formation | |||||
| Common Pathway of Fibrin Clot Formation | |||||
| Gamma-carboxylation of protein precursors | |||||
| Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus | |||||
| Removal of aminoterminal propeptides from gamma-carboxylated proteins | |||||
| References | |||||
| Ref 525658 | Low-molecular-weight heparins in pregnancy. Pharmacotherapy. 1999 Sep;19(9):1013-25. | ||||
| Ref 534676 | Low molecular weight heparins for venous thromboembolism. Drug Ther Bull. 1998 Apr;36(4):25-9. | ||||
| Ref 536361 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. | ||||
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