Drug Information

Drug General Information
Drug ID
D0U9HM
Former ID
DIB016273
Drug Name
GSK-1322888
Synonyms
1322888
Indication Gastroparesis [ICD9: 536.3; ICD10:K31.8] Phase 1 [523354]
Company
GlaxoSmithKline plc
Target and Pathway
Target(s) Motilin receptor Target Info Agonist [523354]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 523354ClinicalTrials.gov (NCT01294566) FTIH to Evaluate Safety, Tolerability, and Pharmacokinetics of Single Oral Doses of GSK1322888 in Healthy Caucasian and Japanese Volunteers. U.S. National Institutes of Health.
Ref 523354ClinicalTrials.gov (NCT01294566) FTIH to Evaluate Safety, Tolerability, and Pharmacokinetics of Single Oral Doses of GSK1322888 in Healthy Caucasian and Japanese Volunteers. U.S. National Institutes of Health.

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