Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0UM7O
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| Former ID |
DAP001148
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| Drug Name |
Ketamine
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| Synonyms |
Calypsol; Cetamina; Green; Ketaject; Ketalar; Ketaminum; Ketanest; Ketoject; Ketolar; Tekam; KETAMINE HCL; Ketalar base; Ketamine Base; Special K; Special K [street name]; CLSTA 20; T385; Cetamina [INN-Spanish]; Dl-Ketamine; Ketalar (TN); Ketamine (INN); Ketamine [INN:BAN]; Ketaminum [INN-Latin]; Ketanest (TN); Ketaset (TN); Tekam (TN); Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)-(9CI); Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)-, (+-)-(9CI); Cyclohexanone, 2-(o-chlorophenyl)-2-(methylamino)-, (+/-)-(8CI); (+-)-Ketamine; (+/-)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone; (+/-)-2-(o-Chlorophenyl)-2-(methylamino)cyclohexanone; (+/-)-Ketamine; 2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone; 2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one; 2-(Methylamino)-2-(2-chlorophenyl)cyclohexanone; 2-(o-Chlorophenyl)-2-(methylamino)-cyclohexanone; 2-(o-Chlorophenyl)-2-(methylamino)cyclohexanone
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| Drug Type |
Small molecular drug
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| Therapeutic Class |
Analgesics
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| Company |
Pfizer Pharmaceuticals
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| Structure |
|
Download2D MOL |
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| Formula |
C13H16ClNO
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| InChI |
InChI=1S/C13H16ClNO/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14/h2-3,6-7,15H,4-5,8-9H2,1H3
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| InChIKey |
YQEZLKZALYSWHR-UHFFFAOYSA-N
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| CAS Number |
CAS 6740-88-1
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| PubChem Compound ID | |||||
| PubChem Substance ID |
9728, 113688, 841263, 5316929, 7979678, 8152419, 10502126, 11335392, 11360631, 11461603, 15220836, 29215438, 29215439, 29222940, 46508295, 48034987, 48416146, 49958360, 53789372, 56424156, 57322007, 77699966, 96024788, 99233266, 103199488, 103975488, 104222089, 104304622, 105600453, 117480213, 118232324, 124813339, 125683401, 129832339, 134338393, 134987353, 137010368, 142340961, 144205256, 144205257, 160964554, 178101050, 179148642, 216074935, 223837115, 226406322, 250059345
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| SuperDrug ATC ID |
N01AX03
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| SuperDrug CAS ID |
cas=006740881
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| Target and Pathway | |||||
| Target(s) | NMDA receptor | Target Info | Antagonist | [536166], [537586], [537702] | |
| References | |||||
| Ref 467569 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4233). | ||||
| Ref 536308 | Calcium channel blockers in the spectrum of antihypertensive agents. Expert Opin Pharmacother. 2006 Dec;7(17):2385-401. | ||||
| Ref 536166 | Glutamate- and GABA-based CNS therapeutics. Curr Opin Pharmacol. 2006 Feb;6(1):7-17. | ||||
| Ref 537586 | Ketamine Modulates Theta and Gamma Oscillations. J Cogn Neurosci. 2009 Jul 7. | ||||
| Ref 537702 | Quantitative studies on some antagonists of N-methyl D-aspartate in slices of rat cerebral cortex. Br J Pharmacol. 1985 Feb;84(2):381-91. | ||||
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