Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0V1SD
|
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| Former ID |
DCL000728
|
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| Drug Name |
BP4.879a
|
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| Drug Type |
Small molecular drug
|
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| Indication | Schizophrenia [ICD9: 295; ICD10:F20] | Terminated | [1] | ||
| Company |
Bioprojet
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C17H22N4O
|
||||
| Canonical SMILES |
CN1C2CCC1CC(C2)NC(=O)C3=NN(C4=CC=CC=C43)C
|
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| InChI |
1S/C17H22N4O/c1-20-12-7-8-13(20)10-11(9-12)18-17(22)16-14-5-3-4-6-15(14)21(2)19-16/h3-6,11-13H,7-10H2,1-2H3,(H,18,22)/t11?,12-,13+
|
||||
| InChIKey |
DDHAJFBBJWHSBR-YHWZYXNKSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | D(3) dopamine receptor | Target Info | Antagonist | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Dopaminergic synapse | |||||
| Reactome | Dopamine receptors | ||||
| G alpha (i) signalling events | |||||
| WikiPathways | Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| Nicotine Activity on Dopaminergic Neurons | |||||
| GPCRs, Other | |||||
| References | |||||
| REF 1 | The pipeline and future of drug development in schizophrenia. Mol Psychiatry. 2007 Oct;12(10):904-22. Epub 2007 Jul 31. | ||||
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