Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0V4JQ
|
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| Former ID |
DAP001282
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| Drug Name |
Interferon beta-1a
|
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| Synonyms |
Avonex; Avonex (TN); Cinnovex (TN); Rebif (TN); Interferon beta-1a (USAN); Interferon beta-1a (genetical recombination); Interferon beta-1a (genetical recombination) (JAN)
|
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| Therapeutic Class |
Immunomodulatory Agents
|
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| Formula |
C908H1408N246O252S7
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| CAS Number |
CAS 145258-61-3
|
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| PubChem Substance ID | |||||
| SuperDrug ATC ID |
L03AB07
|
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| Target and Pathway | |||||
| Target(s) | Interferon beta ligand | Target Info | Modulator | [556264] | |
| KEGG Pathway | Cytokine-cytokine receptor interaction | ||||
| PI3K-Akt signaling pathway | |||||
| Osteoclast differentiation | |||||
| Toll-like receptor signaling pathway | |||||
| RIG-I-like receptor signaling pathway | |||||
| Cytosolic DNA-sensing pathway | |||||
| Jak-STAT signaling pathway | |||||
| Natural killer cell mediated cytotoxicity | |||||
| Chagas disease (American trypanosomiasis) | |||||
| Tuberculosis | |||||
| Hepatitis C | |||||
| Hepatitis B | |||||
| Measles | |||||
| Influenza A | |||||
| Herpes simplex infection | |||||
| NetPath Pathway | TNFalpha Signaling Pathway | ||||
| PANTHER Pathway | Toll receptor signaling pathway | ||||
| Pathway Interaction Database | Regulation of nuclear SMAD2/3 signaling | ||||
| WikiPathways | Toll-like receptor signaling pathway | ||||
| Type II interferon signaling (IFNG) | |||||
| Senescence and Autophagy in Cancer | |||||
| Cytokines and Inflammatory Response | |||||
| EBV LMP1 signaling | |||||
| RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways | |||||
| Interferon alpha/beta signaling | |||||
| Regulation of toll-like receptor signaling pathway | |||||
| Osteoclast Signaling | |||||
| References | |||||
| Ref 536361 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. | ||||
| Ref 543077 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8339). | ||||
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