| Drug General Information |
| Drug ID |
D0V4NQ
|
| Former ID |
DNC002420
|
| Drug Name |
S-Ethylisothiourea
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C3H9BrN2S
|
| Canonical SMILES |
CCSC(=N)N.Br
|
| InChI |
1S/C3H8N2S.BrH/c1-2-6-3(4)5;/h2H2,1H3,(H3,4,5);1H
|
| InChIKey |
SWXXKWPYNMZFTE-UHFFFAOYSA-N
|
| CAS Number |
CAS 2986-20-1
|
| PubChem Compound ID |
|
| PubChem Substance ID |
542880, 607921, 10263850, 14916396, 17405054, 24278413, 24858179, 26612797, 26747505, 26758683, 33519656, 50027114, 50106269, 53777597, 56463506, 57399238, 77087887, 87569473, 89365359, 92304052, 104427846, 117385775, 118195731, 123096438, 125334768, 131389428, 135176767, 160782990, 162252864, 162283510, 162773340, 163564445, 163688160, 163739236, 175612418, 184575947, 204360396, 218911198, 224276912, 225159035, 226408203, 241181943, 251879115, 251893125, 252368855, 252469253, 252499679
|
| Target and Pathway |
| Target(s) |
Nitric oxide synthase, inducible |
Target Info |
Inhibitor |
[1]
|
|---|
|
BioCyc Pathway
|
Citrulline-nitric oxide cycle
|
|
KEGG Pathway
|
Arginine biosynthesis
|
|
Arginine and proline metabolism
|
|
Metabolic pathways
|
|
Calcium signaling pathway
|
|
HIF-1 signaling pathway
|
|
Peroxisome
|
|
Salmonella infection
|
|
Pertussis
|
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Leishmaniasis
|
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Chagas disease (American trypanosomiasis)
|
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Toxoplasmosis
|
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Amoebiasis
|
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Tuberculosis
|
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Pathways in cancer
|
|
Small cell lung cancer
|
|
NetPath Pathway
|
IL1 Signaling Pathway
|
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IL2 Signaling Pathway
|
|
Pathway Interaction Database
|
IL12-mediated signaling events
|
|
Alpha9 beta1 integrin signaling events
|
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ATF-2 transcription factor network
|
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IL23-mediated signaling events
|
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Signaling mediated by p38-alpha and p38-beta
|
|
HIF-1-alpha transcription factor network
|
|
Reactome
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ROS production in response to bacteria
|
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Nitric oxide stimulates guanylate cyclase
|
|
WikiPathways
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Type II interferon signaling (IFNG)
|
|
Spinal Cord Injury
|
|
AGE/RAGE pathway
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|
Effects of Nitric Oxide
|
| References |
| REF 1 | How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. |
|---|
