Drug General Information
Drug ID	D0V7HJ
Former ID	DNC006797
Drug Name	3-[2-(N,N,N-trimethylammonium)ethoxy]pyridine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528245]
Structure		Download 2D MOL 3D MOL
Formula	C10H17N2O+
Canonical SMILES	C[N+](C)(C)CCOC1=CN=CC=C1
InChI	1S/C10H17N2O/c1-12(2,3)7-8-13-10-5-4-6-11-9-10/h4-6,9H,7-8H2,1-3H3/q+1
InChIKey	WBRKKKJHXQZXEM-UHFFFAOYSA-N
PubChem Compound ID	9794401
Target and Pathway
Target(s)	Neuronal acetylcholine receptor protein, beta-2 chain	Target Info	Inhibitor	[528245]
	Neuronal acetylcholine receptor protein, alpha-4 chain	Target Info	Inhibitor	[528245]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Cholinergic synapse
	Nicotine addictionhsa04080:Neuroactive ligand-receptor interaction
	Nicotine addiction
PANTHER Pathway	Nicotinic acetylcholine receptor signaling pathway
	Nicotine pharmacodynamics pathwayP00044:Nicotinic acetylcholine receptor signaling pathway
	Nicotine pharmacodynamics pathway
Reactome	Highly sodium permeable acetylcholine nicotinic receptors
	Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
	Highly calcium permeable nicotinic acetylcholine receptorsR-HSA-629587:Highly sodium permeable acetylcholine nicotinic receptors
	Highly calcium permeable nicotinic acetylcholine receptors
WikiPathways	SIDS Susceptibility Pathways
	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
	Nicotine Activity on Dopaminergic NeuronsWP706:SIDS Susceptibility Pathways
	Nicotine Activity on Dopaminergic Neurons
References
Ref 528245	Bioorg Med Chem Lett. 2006 Aug 15;16(16):4283-6. Epub 2006 Jun 9.Aryloxyethylamines: binding at alpha7 nicotinic acetylcholine receptors.
Ref 528245	Bioorg Med Chem Lett. 2006 Aug 15;16(16):4283-6. Epub 2006 Jun 9.Aryloxyethylamines: binding at alpha7 nicotinic acetylcholine receptors.

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