Drug General Information
Drug ID
D0V8PN
Former ID
DIB006733
Drug Name
Droxinavir hydrochloride
Synonyms
SC-55389; SC-55389A
Indication Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] Terminated [545796]
Company
GD Searle & Co
Structure
Download
2D MOL

3D MOL

Canonical SMILES
C(=O)(N(C[C@H]([C@@H](NC(=O)[C@@H](NC(=O)CNC)C(C)(C)C)C<br />c1ccccc1)O)CCC(C)C)NC(C)(C)C.Cl
CAS Number
CAS 155662-50-3
Target and Pathway
Target(s) HIV protease Target Info Modulator [534332]
References
Ref 545796Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004768)
Ref 534332A mutation in human immunodeficiency virus type 1 protease at position 88, located outside the active site, confers resistance to the hydroxyethylurea inhibitor SC-55389A. Antimicrob Agents Chemother. 1997 Mar;41(3):515-22.

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