Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0V9NE
|
||||
| Former ID |
DNC002674
|
||||
| Drug Name |
Tanaproget
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Estrogen deficiency [ICD10:E28.39] | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C16H15N3OS
|
||||
| InChI |
InChI=1S/C16H15N3OS/c1-16(2)12-8-10(4-6-13(12)18-15(21)20-16)14-7-5-11(9-17)19(14)3/h4-8H,1-3H3,(H,18,21)
|
||||
| InChIKey |
PYVFWTPEBMRKSR-UHFFFAOYSA-N
|
||||
| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Progesterone receptor | Target Info | Inhibitor | [2] | |
| KEGG Pathway | Oocyte meiosis | ||||
| Progesterone-mediated oocyte maturation | |||||
| Pathway Interaction Database | Cellular roles of Anthrax toxin | ||||
| Reactome | Nuclear signaling by ERBB4 | ||||
| Nuclear Receptor transcription pathway | |||||
| WikiPathways | Ovarian Infertility Genes | ||||
| Signaling by ERBB4 | |||||
| Nuclear Receptors | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7416). | ||||
| REF 2 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. | ||||
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