Drug Information

Drug General Information
Drug ID
D0V9YW
Former ID
DPR000057
Drug Name
GYKI-47261
Synonyms
GYKI 47261
Drug Type
Small molecular drug
Indication Parkinson's disease [ICD9: 332; ICD10:G20] Preclinical [536285]
Structure
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2D MOL

3D MOL
Formula
C18H17Cl3N4
Canonical SMILES
CC1=CN2C(=N1)CC3=C(C=C(C=C3)Cl)C(=N2)C4=CC=C(C=C4)N.Cl.<br />Cl
InChI
1S/C18H15ClN4.2ClH/c1-11-10-23-17(21-11)8-13-2-5-14(19)9-16(13)18(22-23)12-3-6-15(20)7-4-12;;/h2-7,9-10H,8,20H2,1H3;2*1H
InChIKey
HUNSEMNKAFDVDI-UHFFFAOYSA-N
CAS Number
CAS 220445-20-5
PubChem Compound ID
46861544
PubChem Substance ID
120898680, 124387208, 134964479, 135698809, 163124404, 204371556, 241376259, 249617760, 252157015
Target and Pathway
Target(s) Glutamate receptor AMPA subtype Target Info Antagonist [536923]
References
Ref 536285Novel pharmacological targets for the treatment of Parkinson's disease. Nat Rev Drug Discov. 2006 Oct;5(10):845-54.
Ref 536923Drugs used to treat Parkinson's disease, present status and future directions. CNS Neurol Disord Drug Targets. 2008 Oct;7(4):321-42.

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