| Drug General Information |
| Drug ID |
D0VF3C
|
| Former ID |
DIB005091
|
| Drug Name |
NPC-01
|
| Synonyms |
LEP pill; Low dose estrogen progestin pill (dysmenorrhea), Nobelpharma
|
| Indication |
Dysmenorrhea [ICD9: 625.3; ICD10:N94.4-N94.6]
|
Phase 3 |
[1]
|
|---|
| Company |
Nobelpharma Co Ltd
|
| Target and Pathway |
| Target(s) |
Estrogen receptor |
Target Info |
Modulator |
[1]
|
|---|
| Progesterone receptor |
Target Info |
Agonist |
[1]
|
|
KEGG Pathway
|
Estrogen signaling pathway
|
|
Prolactin signaling pathway
|
|
Thyroid hormone signaling pathway
|
|
Endocrine and other factor-regulated calcium reabsorption
|
|
Proteoglycans in cancerhsa04114:Oocyte meiosis
|
|
Progesterone-mediated oocyte maturation
|
|
NetPath Pathway
|
FSH Signaling Pathway
|
|
EGFR1 Signaling Pathway
|
|
RANKL Signaling Pathway
|
|
Pathway Interaction Database
|
Regulation of nuclear SMAD2/3 signaling
|
|
Signaling events mediated by HDAC Class II
|
|
Plasma membrane estrogen receptor signaling
|
|
LKB1 signaling events
|
|
Regulation of Telomerase
|
|
ATF-2 transcription factor network
|
|
AP-1 transcription factor network
|
|
FOXM1 transcription factor network
|
|
Validated nuclear estrogen receptor alpha network
|
|
Signaling mediated by p38-alpha and p38-beta
|
|
FOXA1 transcription factor networkanthraxpathway:Cellular roles of Anthrax toxin
|
|
Reactome
|
Nuclear signaling by ERBB4
|
|
Nuclear Receptor transcription pathwayR-HSA-1251985:Nuclear signaling by ERBB4
|
|
Nuclear Receptor transcription pathway
|
|
WikiPathways
|
Estrogen signaling pathway
|
|
Nuclear Receptors Meta-Pathway
|
|
Estrogen Receptor Pathway
|
|
Signaling by ERBB4
|
|
JAK/STAT
|
|
Integrated Pancreatic Cancer Pathway
|
|
Leptin signaling pathway
|
|
miR-targeted genes in muscle cell - TarBase
|
|
Integrated Breast Cancer Pathway
|
|
Nuclear ReceptorsWP34:Ovarian Infertility Genes
|
|
Nuclear Receptors
|
| References |
| REF 1 | ClinicalTrials.gov (NCT01246791) Pharmacokinetics of NPC-01 After Single Oral Administration in Healthy Female Volunteers. U.S. National Institutes of Health. |
|---|
