Drug Information

Drug General Information
Drug ID
D0VH3H
Former ID
DCL001246
Drug Name
TM38837
Drug Type
Small molecular drug
Indication Obesity; Metabolic disorders [ICD9: 270-279, 278; ICD10:E66, E70-E89] Phase 1 [543260], [550186]
Company
7TM Pharma A/S
Structure
Download
2D MOL

3D MOL
Formula
C30H25Cl2F3N4OS
InChI
InChI=1S/C30H25Cl2F3N4OS/c1-2-23-27(29(40)37-38-16-4-3-5-17-38)36-39(25-14-11-21(31)18-24(25)32)28(23)26-15-13-22(41-26)12-8-19-6-9-20(10-7-19)30(33,34)35/h6-7,9-11,13-15,18H,2-5,16-17H2,1H3,(H,37,40)
InChIKey
VQOCBFYUDSBDCZ-UHFFFAOYSA-N
PubChem Compound ID
49779607
PubChem Substance ID
103052067, 162224222, 247561928, 252166905
Target and Pathway
Target(s) Cannabinoid receptor 1 Target Info Antagonist [550186]
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
BDNF signaling pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 543260(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8705).
Ref 5501862011 Pipeline of 7TM Pharma.
Ref 5501862011 Pipeline of 7TM Pharma.

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