Drug Information

Drug General Information
Drug ID
D0VT8P
Former ID
DAP000489
Drug Name
Famciclovir
Synonyms
FCV; Famciclovirum; Famvir; Oravir; BRL 42810; IN1338; Anti-Farnesyl Rabbit pAb; BRL-42810; Famciclovirum [INN-Latin]; Famvir (TN); Famciclovir [USAN:BAN:INN]; Famciclovir (JAN/USAN/INN); [2-(acetyloxymethyl)-4-(2-aminopurin-9-yl)butyl] acetate; Diacetyl 6-deoxy-9-(4-hydroxy-3-hydroxymethyl-but-1-yl)guanine; 1,3-Propanediol, 2-(2-(2-amino-9H-purin-9-yl)ethyl)-, diacetate (ester); 2-(2-(2-Amino-9H-purin-9-yl)ethyl)-1,3-propanediol diacetate (ester); 2-(2-(2-amino-9H-purin-9-yl)ethyl)-1,3-propanediol diacetate; 2-(acetoxymethyl)-4-(2-amino-4,5-dihydro-9H-purin-9-yl)butyl acetate; 2-[(acetyloxy)methyl]-4-(2-amino-9H-purin-9-yl)butyl acetate; 2-[2-(2-amino-9H-purin-9-yl)ethyl]-1,3-propanediol diacetate; 9-(4-acetoxy-3-(acetoxymethyl)but-1-yl)-2-aminopurine; 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine
Drug Type
Small molecular drug
Indication Viral infections [ICD9: 054.0, 054.1, 054.2, 054.3, 075, 771.2, 052, 053; ICD10:B01, B02, A60, B00, B27, G05.1, P35.2] Approved [536361]
Therapeutic Class
Antiviral Agents
Company
Schering-Plough
Structure
Download
2D MOL

3D MOL
Formula
C14H19N5O4
Canonical SMILES
CC(=O)OCC(CCN1C=NC2=CN=C(N=C21)N)COC(=O)C
InChI
1S/C14H19N5O4/c1-9(20)22-6-11(7-23-10(2)21)3-4-19-8-17-12-5-16-14(15)18-13(12)19/h5,8,11H,3-4,6-7H2,1-2H3,(H2,15,16,18)
InChIKey
GGXKWVWZWMLJEH-UHFFFAOYSA-N
CAS Number
CAS 104227-87-4
PubChem Compound ID
3324
PubChem Substance ID
626303, 5276651, 7847383, 7979216, 8152111, 11363360, 11365922, 11368484, 11372808, 11374301, 11376646, 11484938, 11488917, 11491490, 11492426, 11494280, 11528705, 12013946, 14899331, 26612822, 26680213, 26719883, 26748972, 26748973, 26758694, 29222459, 46386745, 46507561, 47291220, 47515410, 48415997, 49681753, 50107498, 52712677, 53800778, 56313627, 57321725, 68530529, 81092805, 85173809, 85787983, 92124793, 92308042, 92308372, 92309126, 92710468, 103158204, 103231964, 104253634, 104303176
SuperDrug ATC ID
J05AB09; S01AD07
SuperDrug CAS ID
cas=104227874
Drug Resistance Mutation (DRM)
DRM DRM Info
Target and Pathway
Target(s) DNA polymerase (HSV-2) Target Info Inhibitor [536009]
References
Ref 536361Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20.
Ref 536009Penciclovir cream--improved topical treatment for herpes simplex infections. Skin Pharmacol Physiol. 2004 Sep-Oct;17(5):214-8.

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