Drug Information

Drug General Information
Drug ID
D0W0XM
Former ID
DIB008540
Drug Name
NPS-2390
Drug Type
Small molecular drug
Indication Cerebrovascular ischaemia [ICD9: 434.91; ICD10:I61-I63] Preclinical [538860], [547300]
Company
NPS Pharmaceuticals Inc
Structure
Download
2D MOL

3D MOL
Formula
C19H21N3O
InChI
InChI=1S/C19H21N3O/c23-18(17-11-20-15-3-1-2-4-16(15)21-17)22-19-8-12-5-13(9-19)7-14(6-12)10-19/h1-4,11-14H,5-10H2,(H,22,23)
InChIKey
ZKFVOZCCAXQXBU-UHFFFAOYSA-N
CAS Number
CAS 226878-01-9
PubChem Compound ID
7067728
PubChem Substance ID
12173498, 17201935, 24741758, 43655600, 47359934, 47954500, 50484815, 85209208, 90695653, 99921038, 103556888, 104055292, 105851404, 114871568, 129914805, 131129481, 134350678, 135650740, 135653822, 162248302, 223794420, 226957418, 252157815
Target and Pathway
Target(s) Extracellular calcium-sensing receptor Target Info Modulator
Pathway Interaction Database E-cadherin signaling in keratinocytes
Reactome G alpha (q) signalling events
G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
WikiPathways GPCRs, Class C Metabotropic glutamate, pheromone
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 538860(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1384).
Ref 547300Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800014988)

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.