TTD | Drug: D0W1BY

Drug General Information
Drug ID	D0W1BY
Former ID	DNC011439
Drug Name	(D)Phe-Gln-Trp-Ala-Val-Gly-His-Leu-Leu-NH2
Indication	Discovery agent		Investigative	[525815]
Structure		Download 2D MOL 3D MOL
Formula	C53H76N14O10
Canonical SMILES	CC(C)CC(C(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CC1=CN=CN1)NC(=O)<br />CNC(=O)C(C(C)C)NC(=O)C(C)NC(=O)C(CC2=CNC3=CC=CC=C32)NC(<br />=O)C(CCC(=O)N)NC(=O)C(CC4=CC=CC=C4)N
InChI	1S/C53H76N14O10/c1-28(2)19-39(46(56)70)64-51(75)40(20-29(3)4)65-52(76)42(23-34-25-57-27-60-34)62-44(69)26-59-53(77)45(30(5)6)67-47(71)31(7)61-50(74)41(22-33-24-58-37-16-12-11-15-35(33)37)66-49(73)38(17-18-43(55)68)63-48(72)36(54)21-32-13-9-8-10-14-32/h8-16,24-25,27-31,36,38-42,45,58H,17-23,26,54H2,1-7H3,(H2,55,68)(H2,56,70)(H,57,60)(H,59,77)(H,61,74)(H,62,69)(H,63,72)(H,64,75)(H,65,76)(H,66,73)(H,67,71)/t31-,36-,38-,39-,40-,41-,42-,45-/m0/s1
InChIKey	HLAREJIMNCKKSS-CENAJWRVSA-N
PubChem Compound ID	44315629
Target and Pathway
Target(s)	Gastrin-releasing peptide receptor	Target Info	Inhibitor	[525815]
KEGG Pathway	Calcium signaling pathway
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Peptide ligand-binding receptors
Reactome	G alpha (q) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Peptide GPCRs
	GPCRs, Other
References
Ref 525815	J Med Chem. 2000 Jun 15;43(12):2356-61.Synthesis and biological evaluation of bombesin constrained analogues.
Ref 525815	J Med Chem. 2000 Jun 15;43(12):2356-61.Synthesis and biological evaluation of bombesin constrained analogues.

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Drug Information