Drug General Information
Drug ID	D0W1JY
Former ID	DNC002405
Drug Name	NAPQI
Drug Type	Small molecular drug
Indication	Refractory autoimmune diseases [ICD9: 279.4; ICD10:D84.9, M35.9]		Investigative	[541449]
Structure		Download 2D MOL 3D MOL
Formula	C8H7NO2
InChI	InChI=1S/C8H7NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5H,1H3
InChIKey	URNSECGXFRDEDC-UHFFFAOYSA-N
PubChem Compound ID	39763
PubChem Substance ID	3157570, 4709584, 8146711, 8176216, 12085919, 14967744, 24891199, 34705623, 49860059, 57312339, 57653880, 74502607, 81065532, 84942668, 103205881, 104332622, 117585715, 125371250, 126602124, 129410431, 135260796, 136345198, 137236550, 142267251, 162078039, 162304369, 178102919, 184560195, 198952612, 204364752, 223516362, 226688208, 252262071, 252354324
Target and Pathway
Target(s)	Macrophage migration inhibitory factor	Target Info	Inhibitor	[529649]
KEGG Pathway	Tyrosine metabolism
	Phenylalanine metabolism
PathWhiz Pathway	Tyrosine Metabolism
WikiPathways	Spinal Cord Injury
	Adipogenesis
References
Ref 541449	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6299).
Ref 529649	MIF in autoimmunity and novel therapeutic approaches. Autoimmun Rev. 2009 Jan;8(3):244-9.

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