Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0W2EK
|
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| Former ID |
DAP001562
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| Drug Name |
Ixabepilone
|
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| Synonyms |
Azaepothilone B; BMS-247550; Ixempra (TN)
|
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| Drug Type |
Small molecular drug
|
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| Company |
Bristol-Myers Squibb
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C27H42N2O5S
|
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| InChI |
InChI=1S/C27H42N2O5S/c1-15-9-8-10-27(7)22(34-27)12-20(16(2)11-19-14-35-18(4)28-19)29-23(31)13-21(30)26(5,6)25(33)17(3)24(15)32/h11,14-15,17,20-22,24,30,32H,8-10,12-13H2,1-7H3,(H,29,31)/b16-11+/t15-,17+,20-,21-,22-,24-,27+/m0/s1
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| InChIKey |
FABUFPQFXZVHFB-PVYNADRNSA-N
|
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| CAS Number |
CAS 219989-84-1
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
11969810, 14786763, 14933557, 34184371, 47206488, 49684213, 49999545, 57369862, 76567192, 91148449, 103771488, 114573104, 126623101, 126665598, 127325936, 127325937, 127325938, 127325939, 134223036, 135135146, 135610851, 137240334, 137248706, 140173305, 152258135, 160646974, 162202446, 175267394, 176484667, 178103430, 179150167, 184022005, 184529017, 184812276, 221678841, 223664545, 226399596, 228058699, 241053227, 248880927, 251910828, 252448545
|
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| SuperDrug ATC ID |
L01DC04
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| Target and Pathway | |||||
| Target(s) | Tubulin | Target Info | Stablizer | [531351] | |
| References | |||||
| Ref 529282 | 2007 FDA drug approvals: a year of flux. Nat Rev Drug Discov. 2008 Feb;7(2):107-9. | ||||
| Ref 531351 | Mullard A: 2010 FDA drug approvals. Nat Rev Drug Discov. 2011 Feb;10(2):82-5. | ||||
| Ref 541906 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6824). | ||||
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