Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0W2PK
|
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| Former ID |
DIB015682
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| Drug Name |
Beloxepin
|
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| Synonyms |
ADL-6906; Beloxepin (oral, pain); Beloxepin (oral, depression), Organon; Beloxepin (oral, pain), Adolor
|
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| Indication | Depression [ICD9: 311; ICD10:F30-F39] | Discontinued in Phase 1 | [1] | ||
| Company |
Adolor Corp; Organon BioSciences
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| Structure |
|
Download2D MOL |
|||
| Canonical SMILES |
O1c2c([C@]3([C@H](CN(CC3)C)c3c1c(ccc3)C)O)cccc2
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| CAS Number |
CAS 135928-30-2
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| Target and Pathway | |||||
| Target(s) | 5-HT 2 receptor | Target Info | Modulator | [2] | |
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Gap junction | |||||
| Serotonergic synapse | |||||
| Inflammatory mediator regulation of TRP channels | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001334) | ||||
| REF 2 | WO patent application no. 2009,1055,07, Beloxepin, its enantiomers, and analogs thereof for the treatment of pain. | ||||
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