TTD | Drug: D0W6GE

Drug General Information
Drug ID	D0W6GE
Former ID	DNC006587
Drug Name	N-(naphthalen-1-yl)-4-neopentylthiazol-2-amine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528047]
Structure		Download 2D MOL 3D MOL
Formula	C18H20N2S
Canonical SMILES	CC(C)(C)CC1=CSC(=N1)NC2=CC=CC3=CC=CC=C32
InChI	1S/C18H20N2S/c1-18(2,3)11-14-12-21-17(19-14)20-16-10-6-8-13-7-4-5-9-15(13)16/h4-10,12H,11H2,1-3H3,(H,19,20)
InChIKey	RIPVNQXJGQJLHV-UHFFFAOYSA-N
PubChem Compound ID	9922232
Target and Pathway
Target(s)	C-Cchemokine receptor type 4	Target Info	Inhibitor	[528047]
KEGG Pathway	Cytokine-cytokine receptor interaction
	Chemokine signaling pathway
	Viral carcinogenesis
PANTHER Pathway	Inflammation mediated by chemokine and cytokine signaling pathway
Reactome	Chemokine receptors bind chemokines
Reactome	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 528047	Bioorg Med Chem Lett. 2006 May 15;16(10):2800-3. Epub 2006 Feb 23.Optimization of 2-aminothiazole derivatives as CCR4 antagonists.
Ref 528047	Bioorg Med Chem Lett. 2006 May 15;16(10):2800-3. Epub 2006 Feb 23.Optimization of 2-aminothiazole derivatives as CCR4 antagonists.

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Drug Information