Drug Information
Drug General Information | |||||
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Drug ID |
D0W8XT
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Former ID |
DIB000683
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Drug Name |
Mibefradil
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Synonyms |
Mibefradil (Cytostatic Checkpoint Therapy, ovarian cancer); Mibefradil (Cytostatic Checkpoint Therapy, ovarian cancer), Tau Therapeutics; Calcium T-channel inhibitor (Cytostatic Checkpoint Therapy, ovarian cancer), Tau Therapeutics
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Drug Type |
Small molecular drug
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Company |
Tau therapeutics; cavion
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Structure |
Download2D MOL |
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Formula |
C29H38FN3O3
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InChI |
InChI=1S/C29H38FN3O3/c1-20(2)28-23-12-11-22(30)18-21(23)13-14-29(28,36-27(34)19-35-4)15-17-33(3)16-7-10-26-31-24-8-5-6-9-25(24)32-26/h5-6,8-9,11-12,18,20,28H,7,10,13-17,19H2,1-4H3,(H,31,32)/t28-,29-/m0/s1
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InChIKey |
HBNPJJILLOYFJU-VMPREFPWSA-N
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CAS Number |
CAS 116644-53-2
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PubChem Compound ID | |||||
PubChem Substance ID |
9431, 7979984, 8186987, 11111472, 14933121, 14933122, 26755047, 43118024, 46504498, 47276715, 48416277, 50064211, 50110875, 51068792, 53788328, 53801058, 57314055, 85788182, 90340964, 96024905, 103229908, 104011327, 104321323, 117509413, 124749965, 128037075, 134338995, 135047604, 137006402, 142794297, 160964663, 163620961, 163686283, 176250376, 179149650, 185998774, 198963086, 215784885, 223440331, 223554765, 225039582, 226424915, 242060284, 250133489, 251971143, 252479748, 252655656
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Target and Pathway | |||||
Target(s) | Voltage-dependent T-type calcium channel subunit alpha-1H | Target Info | Inhibitor | [525870] | |
PathWhiz Pathway | Muscle/Heart Contraction | ||||
Reactome | NCAM1 interactions | ||||
References | |||||
Ref 539642 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2522). | ||||
Ref 544589 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000236) |
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